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Multiple essential MT1-MMP functions in tooth root formation, dentinogenesis, and tooth eruption

Membrane-type matrix metalloproteinase 1 (MT1-MMP) is a transmembrane zinc-endopeptidase that breaks down extracellular matrix components, including several collagens, during tissue development and physiological remodeling. MT1-MMP-deficient mice (MT1-MMP(−/−)) feature severe defects in connective t...

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Detalles Bibliográficos
Publicado en:Matrix Biol
Main Authors: Xu, H., Snider, T.N., Wimer, H.F., Yamada, S.S., Yang, T., Holmbeck, K., Foster, B.L.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875876/
https://ncbi.nlm.nih.gov/pubmed/26780723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2016.01.002
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