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Atomic features of an autoantigen in heparin-induced thrombocytopenia (HIT)
Autoantigen development is poorly understood at the atomic level. Heparin-induced thrombocytopenia (HIT) is an autoimmune thrombotic disorder caused by antibodies to an antigen composed of platelet factor 4 (PF4) and heparin or cellular glycosaminoglycans (GAGs). In solution, PF4 exists as an equili...
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| Veröffentlicht in: | Autoimmun Rev |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875785/ https://ncbi.nlm.nih.gov/pubmed/26970483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autrev.2016.03.011 |
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