Influence of mTOR-inhibitors and mycophenolic acid on human cholangiocellular carcinoma and cancer associated fibroblasts

BACKGROUND: The incidence of Cholangiocellular Carcinoma (CCA) is increasing in the western world. The tumour has a high proportion of desmoplastic stroma and is correlated with a worse prognosis when cancer associated myofibroblasts (CAFs) are present. Recent studies showed promising results after...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Heits, Nils, Heinze, Tillmann, Bernsmeier, Alexander, Kerber, Jannik, Hauser, Charlotte, Becker, Thomas, Kalthoff, Holger, Egberts, Jan-Hendrik, Braun, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875636/
https://ncbi.nlm.nih.gov/pubmed/27206490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2360-8
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