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Toward pluripotency by reprogramming: mechanisms and application
The somatic epigenome can be reprogrammed to a pluripotent state by a combination of transcription factors. Altering cell fate involves transcription factors cooperation, epigenetic reconfiguration, such as DNA methylation and histone modification, posttranscriptional regulation by microRNAs, and so...
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Publié dans: | Protein Cell |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Higher Education Press
2013
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875451/ https://ncbi.nlm.nih.gov/pubmed/24078387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-3074-1 |
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