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An open conformation determined by a structural switch for 2A protease from coxsackievirus A16

Coxsackievirus A16 belongs to the family Picornaviridae, and is a major agent of hand-foot-and-mouth disease that infects mostly children, and to date no vaccines or antiviral therapies are available. 2A protease of enterovirus is a nonstructural protein and possesses both self-cleavage activity and...

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Bibliographische Detailangaben
Veröffentlicht in:Protein Cell
Hauptverfasser: Sun, Yao, Wang, Xiangxi, Yuan, Shuai, Dang, Minghao, Li, Xuemei, Zhang, Xuejun C., Rao, Zihe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Higher Education Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875437/
https://ncbi.nlm.nih.gov/pubmed/24026848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-3914-z
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