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Multifaceted functions of Siva-1: more than an Indian God of Destruction

Siva-1, as a p53-inducible gene, has been shown to induce extensive apoptosis in a number of different cell lines. Recent evidence suggests that Siva-1 functions as a part of the auto-regulatory feedback loop that restrains p53 through facilitating Mdm2-mediated p53 degradation. Also, Siva-1 plays a...

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Vydáno v:Protein Cell
Hlavní autoři: Mei, Yide, Wu, Mian
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875415/
https://ncbi.nlm.nih.gov/pubmed/22426980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-012-2018-5
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