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Microvesicle-delivery miR-150 promotes tumorigenesis by up-regulating VEGF, and the neutralization of miR-150 attenuate tumor development

Tumor-associated macrophages (TAMs) mostly exhibit M2-like (alternatively activated) properties and play positive roles in angiogenesis and tumorigenesis. Vascular endothelial growth factor (VEGF) is a key angiogenic factor. During tumor development, TAMs secrete VEGF and other factors to promote an...

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Détails bibliographiques
Publié dans:Protein Cell
Auteurs principaux: Liu, Yuchen, Zhao, Luming, Li, Dameng, Yin, Yuan, Zhang, Chen-Yu, Li, Jing, Zhang, Yujing
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875402/
https://ncbi.nlm.nih.gov/pubmed/24203759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-013-3092-z
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