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Crystal structure of the C-terminal domain of the ɛ subunit of human translation initiation factor eIF2B

Eukaryotic translation initiation factor eIF2B, the guanine nucleotide exchange factor (GEF) for eIF2, catalyzes conversion of eIF2·GDP to eIF2·GTP. The eIF2B is composed of five subunits, α, β, γ, δ and ɛ, within which the ɛ subunit is responsible for catalyzing the guanine exchange reaction. Here...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Wei, Jia, Jia, Minze, Zhang, Cheng, Wang, Mingzhu, Gao, Feng, Xu, Hang, Gong, Weimin
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875318/
https://ncbi.nlm.nih.gov/pubmed/21204011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0070-6
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