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Structural insight into substrate specificity of human intestinal maltase-glucoamylase

Human maltase-glucoamylase (MGAM) hydrolyzes linear alpha-1,4-linked oligosaccharide substrates, playing a crucial role in the production of glucose in the human lumen and acting as an efficient drug target for type 2 diabetes and obesity. The amino- and carboxyl-terminal portions of MGAM (MGAM-N an...

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Detalles Bibliográficos
Publicado en:Protein Cell
Main Authors: Ren, Limei, Qin, Xiaohong, Cao, Xiaofang, Wang, Lele, Bai, Fang, Bai, Gang, Shen, Yuequan
Formato: Artigo
Idioma:Inglês
Publicado: Higher Education Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875297/
https://ncbi.nlm.nih.gov/pubmed/22058037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1105-3
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