hNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNA

Human NUDT16 (hNUDT16) is a decapping enzyme initially identified as the human homolog to the Xenopus laevis X29. As a metalloenzyme, hNUDT16 relies on divalent cations for its cap-hydrolysis activity to remove m(7)GDP and m(227)GDP from RNAs. Metal also determines substrate specificity of the enzym...

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Publicado en:Protein Cell
Autores principales: Lu, Guangwen, Zhang, Jie, Li, Yan, Li, Zhixin, Zhang, Na, Xu, Xiang, Wang, Tingting, Guan, Zhenhong, Gao, George F., Yan, Jinghua
Formato: Artigo
Lenguaje:Inglês
Publicado: Higher Education Press 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875290/
https://ncbi.nlm.nih.gov/pubmed/21337011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1009-2
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