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ERp44 C160S/C212S mutants regulate IP(3)R(1) channel activity

Previous studies have indicated that ERp44 inhibits inositol 1,4,5-trisphosphate (IP(3))-induced Ca(2+) release (IICR) via IP(3)R(1), but the mechanism remains largely unexplored. Using extracellular ATP to induce intracellular calcium transient as an IICR model, Ca(2+) image, pull down assay, and W...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Pan, Congyan, Zheng, Ji, Wu, Yanyun, Chen, Yingxiao, Wang, Likun, Zhou, Zhansong, Yin, Wenxuan, Ji, Guangju
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875245/
https://ncbi.nlm.nih.gov/pubmed/22183808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1116-0
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