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Crystal structure of a novel non-Pfam protein PF2046 solved using low resolution B-factor sharpening and multi-crystal averaging methods

Sometimes crystals cannot diffract X-rays beyond 3.0 Å resolution due to the intrinsic flexibility associated with the protein. Low resolution diffraction data not only pose a challenge to structure determination, but also hamper interpretation of mechanistic details. Crystals of a 25.6 kDa non-Pfam...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Protein Cell
Hauptverfasser: Su, Jing, Li, Yang, Shaw, Neil, Zhou, Weihong, Zhang, Min, Xu, Hao, Wang, Bi-Cheng, Liu, Zhi-Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Higher Education Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4875130/
https://ncbi.nlm.nih.gov/pubmed/21203960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0045-7
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