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SUMOylation of RIG-I positively regulates the type I interferon signaling
Retinoic acid-inducible gene-I (RIG-I) functions as an intracellular pattern recognition receptor (PRR) that recognizes the 5’-triphosphate moiety of single-stranded RNA viruses to initiate the innate immune response. Previous studies have shown that Lys63-linked ubiquitylation is required for RIG-I...
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| Publicado no: | Protein Cell |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Higher Education Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4875083/ https://ncbi.nlm.nih.gov/pubmed/21203974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-010-0030-1 |
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