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Interleukin (IL)-2 and IL-3 induce distinct but overlapping responses in murine IL-3-dependent 32D cells transduced with human IL-2 receptor beta chain: involvement of tyrosine kinase(s) other than p56lck.

We have established IL-3-dependent 32D myeloid progenitor cells stably expressing the human IL-2 receptor beta chain (IL-2R beta). Whereas parental 32D cells proliferated only in response to IL-3, the transduced cells also proliferated in response to IL-2. Transduced cells expressed high- and interm...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Otani, H, Siegel, J P, Erdos, M, Gnarra, J R, Toledano, M B, Sharon, M, Mostowski, H, Feinberg, M B, Pierce, J H, Leonard, W J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48748/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557384/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2789
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