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Size Selectivity of Intestinal Mucus to Diffusing Particulates is Dependent on Surface Chemistry and Exposure to Lipids

Intestinal mucus provides a significant barrier to transport of orally delivered drug carriers, as well as other particulates (e.g., food, microbes). The relative significance of particle size, surface chemistry, and dosing medium to mucus barrier properties is not well characterized but important i...

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Detalhes bibliográficos
Publicado no:J Drug Target
Main Authors: Yildiz, Hasan M., McKelvey, Craig A., Marsac, Patrick J., Carrier, Rebecca L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874559/
https://ncbi.nlm.nih.gov/pubmed/26453172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2015.1086359
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