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PRODUCTION OF PROINFLAMMATORY CYTOKINES BY MONOCYTES IN LIVER TRANSPLANTED RECIPIENTS WITH DE NOVO AUTOIMMUNE HEPATITIS IS ENHANCED AND INDUCES T(H)1-LIKE REGULATORY T CELLS
A subset of human regulatory T cells (Tregs) can secrete IFN-γ or IL-17 and thus share features of T(H)1 or T(H)17 effector cells, and lose suppressive function. The main factors driving this differentiation of Tregs towards a pro-inflammatory phenotype include IL-12 for T(H)1-like and IL-6 for T(H)...
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| Опубликовано в: : | J Immunol |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4874532/ https://ncbi.nlm.nih.gov/pubmed/27183637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502276 |
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