Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats

BACKGROUND: Hibernation is an adaptation to extreme environments known to provide organ protection against ischemia-reperfusion (I/R) injury. An unbiased systems approach was utilized to investigate hibernation-induced changes characteristic of the hibernator cardioprotective phenotype, by comparing...

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Veröffentlicht in:Anesthesiology
Hauptverfasser: Quinones, Quintin J., Zhang, Zhiquan, Ma, Qing, Smith, Michael P., Soderblom, Erik, Moseley, M. Arthur, Bain, James, Newgard, Christopher B., Muehlbauer, Michael J., Hirschey, Matthew, Drew, Kelly L., Barnes, Brian M., Podgoreanu, Mihai V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874524/
https://ncbi.nlm.nih.gov/pubmed/27187119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001113
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