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Regional signals in the planarian body guide stem cell fate in the presence of genomic instability

Cellular fate decisions are influenced by their topographical location in the adult body. For instance, tissue repair and neoplastic growth are greater in anterior than in posterior regions of adult animals. However, the molecular underpinnings of these regional differences are unknown. We identifie...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Peiris, T. Harshani, Ramirez, Daniel, Barghouth, Paul G., Ofoha, Udokanma, Davidian, Devon, Weckerle, Frank, Oviedo, Néstor J.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874482/
https://ncbi.nlm.nih.gov/pubmed/27013241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.131318
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