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Antimicrobial combinations: Bliss independence and Loewe additivity derived from mechanistic multi-hit models

Antimicrobial peptides (AMPs) and antibiotics reduce the net growth rate of bacterial populations they target. It is relevant to understand if effects of multiple antimicrobials are synergistic or antagonistic, in particular for AMP responses, because naturally occurring responses involve multiple A...

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Détails bibliographiques
Publié dans:Philos Trans R Soc Lond B Biol Sci
Auteurs principaux: Baeder, Desiree Y., Yu, Guozhi, Hozé, Nathanaël, Rolff, Jens, Regoes, Roland R.
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874391/
https://ncbi.nlm.nih.gov/pubmed/27160596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2015.0294
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