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Genetics of Type 1 Diabetes

BACKGROUND: Type 1 diabetes, a multifactorial disease with a strong genetic component, is caused by the autoimmune destruction of pancreatic β cells. The major susceptibility locus maps to the HLA class II genes at 6p21, although more than 40 non-HLA susceptibility gene markers have been confirmed....

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Détails bibliographiques
Publié dans:Clin Chem
Auteurs principaux: Steck, Andrea K., Rewers, Marian J.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874193/
https://ncbi.nlm.nih.gov/pubmed/21205883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2010.148221
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