Adrenal-derived 11-Oxygenated 19-Carbon Steroids are the Dominant Androgens in Classic 21-Hydroxylase Deficiency

OBJECTIVE: To comprehensively characterize androgens and androgen precursors in classic 21-hydroxylase deficiency (21OHD) and to gain insight to the mechanisms of their formation. DESIGN: Serum samples were obtained from 38 patients (19 men) with classic 21OHD, age 3-59, and 38 sex- and age-matched...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur J Endocrinol
Prif Awduron: Turcu, Adina F., Nanba, Aya T., Chomic, Robert, Upadhyay, Sunil K., Giordano, Thomas J., Shields, James J., Merke, Deborah P., Rainey, William E., Auchus, Richard J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4874183/
https://ncbi.nlm.nih.gov/pubmed/26865584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EJE-15-1181
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