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Knockout of ho-1 protects the striatum from ferrous iron-induced injury in a male-specific manner in mice
Men have worse survival than premenopausal women after intracerebral hemorrhage (ICH). After ICH, overproduction of iron associated with induction of heme oxygenase-1 (HO-1) in brain was observed. Rodent ICH model using ferrous citrate (FC)-infusion into the striatum to simulate iron overload, showe...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4873828/ https://ncbi.nlm.nih.gov/pubmed/27198537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26358 |
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