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Functional characterization of a hybrid human-mouse interferon gamma receptor: evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer.

The human interferon gamma (IFN-gamma) receptor expressed in mouse cells displays binding properties indistinguishable from those of the resident receptor on human cells. Still, mouse cells expressing the human IFN-gamma receptor remain insensitive to human IFN-gamma. It is widely accepted that at l...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Hemmi, S, Merlin, G, Aguet, M
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48737/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1532657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2737
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