Accelerating rates of cognitive decline and imaging markers associated with β-amyloid pathology

OBJECTIVE: To estimate points along the spectrum of β-amyloid pathology at which rates of change of several measures of neuronal injury and cognitive decline begin to accelerate. METHODS: In 460 patients with mild cognitive impairment (MCI), we estimated the points at which rates of florbetapir PET,...

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Veröffentlicht in:Neurology
Hauptverfasser: Insel, Philip S., Mattsson, Niklas, Mackin, R. Scott, Schöll, Michael, Nosheny, Rachel L., Tosun, Duygu, Donohue, Michael C., Aisen, Paul S., Jagust, William J., Weiner, Michael W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Lippincott Williams & Wilkins 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873684/
https://ncbi.nlm.nih.gov/pubmed/27164667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000002683
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