Aging Reduces L-Type Calcium Channel Current and the Vasodilatory Response of Small Mesenteric Arteries to Calcium Channel Blockers

Calcium channel blockers (CCBs) are widely used to treat cardiovascular disease (CVD) including hypertension. As aging is an independent risk factor for CVD, the use of CCBs increases with increasing age. Hence, this study was designed to evaluate the effect of aging on the sensitivity of small mese...

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Bibliographic Details
Published in:Front Physiol
Main Authors: Albarwani, Sulayma A., Mansour, Fathi, Khan, Abdul Aleem, Al-Lawati, Intisar, Al-Kaabi, Abdulla, Al-Busaidi, Al-Manar, Al-Hadhrami, Safa, Al-Husseini, Isehaq, Al-Siyabi, Sultan, Tanira, Musbah O.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Physiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873501/
https://ncbi.nlm.nih.gov/pubmed/27242545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2016.00171
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