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Elucidation of the roles of tumor integrin β1 in the extravasation stage of the metastasis cascade

Tumor integrin β1 (ITGB1) contributes to primary tumor growth and metastasis, but its specific roles have yet been clearly elucidated. In this study, we engineered an three-dimensional microfluidic model of the human microvasculature to recapitulate the environment wherein extravasation takes place...

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Foilsithe in:Cancer Res
Main Authors: Chen, Michelle B., Lamar, John M., Li, Ran, Hynes, Richard O., Kamm, Roger D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873393/
https://ncbi.nlm.nih.gov/pubmed/26988988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1325
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