Histone Deacetylase Inhibitors Enhance the Therapeutic Potential of Reovirus in Multiple Myeloma

Multiple myeloma (MM) remains incurable and the majority of patients die within 5 years of diagnosis. Reolysin, the infusible form of human reovirus (RV), is a novel viral oncolytic therapy associated with antitumor activity likely resulting from direct oncolysis and a virus-mediated antitumor immun...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Stiff, Andrew, Caserta, Enrico, Sborov, Douglas W., Nuovo, Gerard J., Mo, Xiaokui, Schlotter, Sarah Y., Canella, Alessandro, Smith, Emily, Badway, Joseph, Old, Matthew, Jaime-Ramirez, Alena Cristina, Yan, Pearlly, Benson, Don M., Byrd, John C., Baiocchi, Robert, Kaur, Balveen, Hofmeister, Craig C., Pichiorri, Flavia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873335/
https://ncbi.nlm.nih.gov/pubmed/26809490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0240-T
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