Assessment of multifactor gene-environment interactions and ovarian cancer risk: Candidate genes, obesity, and hormone-related risk factors

BACKGROUND: Many epithelial ovarian cancer (EOC) risk factors relate to hormone exposure, and elevated estrogen levels are associated with obesity in post-menopausal women. Therefore, we hypothesized that gene-environment interactions related to hormone-related risk factors could differ between obes...

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Publicado en:Cancer Epidemiol Biomarkers Prev
Autores principales: Usset, Joseph L, Raghavan, Rama, Tyrer, Jonathan P, McGuire, Valerie, Sieh, Weiva, Webb, Penelope, Chang-Claude, Jenny, Rudolph, Anja, Anton-Culver, Hoda, Berchuck, Andrew, Brinton, Louise, Cunningham, Julie M, DeFazio, Anna, Doherty, Jennifer A, Edwards, Robert P, Gayther, Simon A, Gentry-Maharaj, Aleksandra, Goodman, Marc T, Høgdall, Estrid, Jensen, Allan, Johnatty, Sharon E, Kiemeney, Lambertus A, Kjaer, Susanne K, Larson, Melissa C, Lurie, Galina, Massuger, Leon, Menon, Usha, Modugno, Francesmary, Moysich, Kirsten B, Ness, Roberta B, Pike, Malcolm C, Ramus, Susan J, Rossing, Mary Anne, Rothstein, Joseph, Song, Honglin, Thompson, Pamela J, van den Berg, David J., Vierkant, Robert A, Wang-Gohrke, Shan, Wentzensen, Nicolas, Whittemore, Alice S, Wilkens, Lynne R, Wu, Anna H, Yang, Hannah, Pearce, Celeste L, Schildkraut, Joellen M, Pharoah, Paul, Goode, Ellen L, Fridley, Brooke L
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873330/
https://ncbi.nlm.nih.gov/pubmed/26976855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-1039
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