The EGF receptor promotes the malignant potential of glioma by regulating amino acid transport system xc(−)

Extracellular free amino acids contribute to the interaction between a tumor and its microenvironment through effects on cellular metabolism and malignant behavior. System xc(−) is composed of xCT and CD98hc subunits and functions as a plasma membrane antiporter for the uptake of extracellular cysti...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Cancer Res
Autores principales: Tsuchihashi, Kenji, Okazaki, Shogo, Ohmura, Mitsuyo, Ishikawa, Miyuki, Sampetrean, Oltea, Onishi, Nobuyuki, Wakimoto, Hiroaki, Yoshikawa, Momoko, Seishima, Ryo, Iwasaki, Yoshimi, Morikawa, Takayuki, Abe, Shinya, Takao, Ayumi, Shimizu, Misato, Masuko, Takashi, Nagane, Motoo, Furnari, Frank, Akiyama, Tetsu, Suematsu, Makoto, Baba, Eishi, Akashi, Koichi, Saya, Hideyuki, Nagano, Osamu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873328/
https://ncbi.nlm.nih.gov/pubmed/26980765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2121
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares