MiR-26a enhances miRNA biogenesis by targeting Lin28B and Zcchc11 to suppress tumor growth and metastasis

Human cancers often exhibit attenuated miRNA biogenesis and global underexpression of miRNAs, thus targeting the miRNA biogenesis pathway represents a novel strategy for cancer therapy. Here, we report that miR-26a enhances miRNA biogenesis, which acts as a common mechanism partially accounting for...

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Publicado no:Oncogene
Main Authors: Fu, Xianghui, Meng, Zhipeng, Liang, Wei, Tian, Yan, Wang, Xichun, Han, Weidong, Lou, Guiyu, Wang, Xiaoqiong, Lou, Fang, Yen, Yun, Yu, Hua, Jove, Richard, Huang, Wendong
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873289/
https://ncbi.nlm.nih.gov/pubmed/24056962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.385
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