Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis

MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized that genetic variations in miRNAs that regula...

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Vydáno v:PLoS One
Hlavní autoři: Lin, Xiaoping, Steinberg, Steven, Kandasamy, Suresh K., Afzal, Junaid, Mbiyangandu, Blaid, Liao, Susan E., Guan, Yufan, Corona-Villalobos, Celia P., Matkovich, Scot J., Epstein, Neal, Tripodi, Dotti, Huo, Zhaoxia, Cutting, Garry, Abraham, Theodore P., Fukunaga, Ryuya, Abraham, M. Roselle
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873136/
https://ncbi.nlm.nih.gov/pubmed/27196440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156065
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