Deletion of LOX-1 Protects against Heart Failure Induced by Doxorubicin

Oxidative stress is one of the major factors in doxorubicin (DOX)-induced cardiomyopathy. Lectin-like oxidized low-density lipoprotein (oxLDL) receptor-1 (LOX-1) plays an important role to regulate cardiac remodeling and oxidative stress after ischemia-reperfusion. Therefore, we examined whether or...

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Udgivet i:PLoS One
Main Authors: Yokoyama, Chiharu, Aoyama, Takuma, Ido, Takahiro, Kakino, Akemi, Shiraki, Takeru, Tanaka, Toshiki, Nishigaki, Kazuhiko, Hasegawa, Aiko, Fujita, Yoshiko, Sawamura, Tatsuya, Minatoguchi, Shinya
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873018/
https://ncbi.nlm.nih.gov/pubmed/27195769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154994
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