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An Integrated Data Driven Approach to Drug Repositioning Using Gene-Disease Associations

Drug development is both increasing in cost whilst decreasing in productivity. There is a general acceptance that the current paradigm of R&D needs to change. One alternative approach is drug repositioning. With target-based approaches utilised heavily in the field of drug discovery, it becomes...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Mullen, Joseph, Cockell, Simon J., Woollard, Peter, Wipat, Anil
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873016/
https://ncbi.nlm.nih.gov/pubmed/27196054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155811
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