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Blockade of Extracellular ATP Effect by Oxidized ATP Effectively Mitigated Induced Mouse Experimental Autoimmune Uveitis (EAU)

Various pathological conditions are accompanied by ATP release from the intracellular to the extracellular compartment. Extracellular ATP (eATP) functions as a signaling molecule by activating purinergic P2 purine receptors. The key P2 receptor involved in inflammation was identified as P2X7R. Recen...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhao, Ronglan, Liang, Dongchun, Sun, Deming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873015/
https://ncbi.nlm.nih.gov/pubmed/27196432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155953
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