Crosstalk between ATF4 and MTA1/HDAC1 promotes osteosarcoma progression

The stress response gene activating transcription factor 4 (ATF4) is involved in metastatic behavior and cellular protection. Here we show that ATF4 is upregulated in osteosarcoma (OS) cell lines and patient clinical samples as compared to matched non-tumor tissue. Overexpression of ATF4 in OS cells...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Zeng, Heng, Zhang, Jin-ming, Du, Yu, Wang, Jiang, Ren, Ye, Li, Mi, Li, Hao, Cai, Zhuo, Chu, Qian, Yang, Caihong
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872789/
https://ncbi.nlm.nih.gov/pubmed/26797758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6940
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