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4-Methoxydalbergione suppresses growth and induces apoptosis in human osteosarcoma cells in vitro and in vivo xenograft model through down-regulation of the JAK2/STAT3 pathway

Although the heartwood of Dalbergia odorifera T. Chen (Leguminosae) is an important source of traditional Korean and Chinese medicines, the effects of novel compound methoxydalbergione (4-MD) isolated from Dalbergia odorifera was not reported. Herein, we investigated the effects of the 4-MD in vitro...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Park, Kyung-Ran, Yun, Hyung-Mun, Quang, Tran-Hong, Oh, Hyuncheol, Lee, Dong-Sung, Auh, Q-Schick, Kim, Eun-Cheol
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872761/
https://ncbi.nlm.nih.gov/pubmed/26755649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6873
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