EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells

Sesquiterpene lactones (SLs) are the active constituents of a variety of medicinal plants and found to have potential anticancer activities. However, the intracellular molecular targets of SLs and the underlying molecular mechanisms have not been well elucidated. In this study, we observed that EM23...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shao, Fang-Yuan, Wang, Sheng, Li, Hong-Yu, Chen, Wen-Bo, Wang, Guo-Cai, Ma, Dong-Lei, Wong, Nai Sum, Xiao, Hao, Liu, Qiu-Ying, Zhou, Guang-Xiong, Li, Yao-Lan, Li, Man-Mei, Wang, Yi-Fei, Liu, Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872749/
https://ncbi.nlm.nih.gov/pubmed/26758418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6828
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