ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells

Posttranslational modifications (PTMs), such as phosphorylation and ubiquitination, play critical regulatory roles in the assembly of DNA damage response proteins on the DNA damage site and their activities in DNA damage repair. Tyrosyl DNA phosphodiesterase 2 (TDP2) repairs Topoisomerase 2 (Top2)-l...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Bian, Ka, Muppani, Naveen Reddy, Elkhadragy, Lobna, Wang, Wei, Zhang, Cheng, Chen, Tenghui, Jung, Sungyun, Seternes, Ole Morten, Long, Weiwen
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872741/
https://ncbi.nlm.nih.gov/pubmed/26701725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6682
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