ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells

Posttranslational modifications (PTMs), such as phosphorylation and ubiquitination, play critical regulatory roles in the assembly of DNA damage response proteins on the DNA damage site and their activities in DNA damage repair. Tyrosyl DNA phosphodiesterase 2 (TDP2) repairs Topoisomerase 2 (Top2)-l...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bian, Ka, Muppani, Naveen Reddy, Elkhadragy, Lobna, Wang, Wei, Zhang, Cheng, Chen, Tenghui, Jung, Sungyun, Seternes, Ole Morten, Long, Weiwen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872741/
https://ncbi.nlm.nih.gov/pubmed/26701725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6682
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