ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells

Posttranslational modifications (PTMs), such as phosphorylation and ubiquitination, play critical regulatory roles in the assembly of DNA damage response proteins on the DNA damage site and their activities in DNA damage repair. Tyrosyl DNA phosphodiesterase 2 (TDP2) repairs Topoisomerase 2 (Top2)-l...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Bian, Ka, Muppani, Naveen Reddy, Elkhadragy, Lobna, Wang, Wei, Zhang, Cheng, Chen, Tenghui, Jung, Sungyun, Seternes, Ole Morten, Long, Weiwen
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872741/
https://ncbi.nlm.nih.gov/pubmed/26701725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6682
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