ERK3 regulates TDP2-mediated DNA damage response and chemoresistance in lung cancer cells

Posttranslational modifications (PTMs), such as phosphorylation and ubiquitination, play critical regulatory roles in the assembly of DNA damage response proteins on the DNA damage site and their activities in DNA damage repair. Tyrosyl DNA phosphodiesterase 2 (TDP2) repairs Topoisomerase 2 (Top2)-l...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Bian, Ka, Muppani, Naveen Reddy, Elkhadragy, Lobna, Wang, Wei, Zhang, Cheng, Chen, Tenghui, Jung, Sungyun, Seternes, Ole Morten, Long, Weiwen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872741/
https://ncbi.nlm.nih.gov/pubmed/26701725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6682
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