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Structure and function of the telomeric CST complex

Telomeres comprise the ends of eukaryotic chromosomes and are essential for cell proliferation and genome maintenance. Telomeres are replicated by telomerase, a ribonucleoprotein (RNP) reverse transcriptase, and are maintained primarily by nucleoprotein complexes such as shelterin (TRF1, TRF2, TIN2,...

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Библиографические подробности
Опубликовано в: :Comput Struct Biotechnol J
Главные авторы: Rice, Cory, Skordalakes, Emmanuel
Формат: Artigo
Язык:Inglês
Опубликовано: Research Network of Computational and Structural Biotechnology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872678/
https://ncbi.nlm.nih.gov/pubmed/27239262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2016.04.002
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