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Targeting of the pulmonary capillary vascular niche promotes lung alveolar repair and ameliorates fibrosis

Although the lung can undergo self-repair after injury, fibrosis in chronically injured or diseased lungs can occur at the expense of regeneration. Here we study how a hematopoietic-vascular niche regulates alveolar repair and lung fibrosis. Using intratracheal injection of bleomycin or hydrochloric...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Med
Hauptverfasser: Cao, Zhongwei, Lis, Raphael, Ginsberg, Michael, Chavez, Deebly, Shido, Koji, Rabbany, Sina Y., Fong, Guo-Hua, Sakmar, Thomas P., Rafii, Shahin, Ding, Bi-Sen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872630/
https://ncbi.nlm.nih.gov/pubmed/26779814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4035
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