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Murine monoclonal anti-idiotope antibody breaks unresponsiveness and induces a specific antibody response to human melanoma-associated proteoglycan antigen in cynomolgus monkeys.

The mouse monoclonal antibody MEM136 (mAb1) is directed against an epitope on human melanoma-associated proteoglycan antigen (MPG). This epitope is also present on various normal human and subhuman tissues. A monoclonal murine anti-idiotope (anti-Id) antibody (mAb2), designated I-Mel-2, was generate...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chattopadhyay, P, Starkey, J, Morrow, W J, Raychaudhuri, S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48726/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1557374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.2684
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