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Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family

Posttranslational regulation of protein function is an ubiquitous mechanism in eukaryotic cells. Here, we analyzed biological properties of nodes and edges of a human protein-protein interaction phosphorylation-based network, especially of those nodes critical for the network controllability. We fou...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Uhart, Marina, Flores, Gabriel, Bustos, Diego M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872533/
https://ncbi.nlm.nih.gov/pubmed/27195976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26234
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