Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes

OBJECTIVE: Genes that modulate insulin sensitivity may also be involved in shaping the risk of coronary artery disease (CAD). The relatively common TRIB3 Q84R polymorphism (rs2295490) has been associated with abnormal insulin signaling, endothelial dysfunction, insulin resistance, and pro-atherogeni...

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Publicado en:Atherosclerosis
Autores principales: Prudente, Sabrina, Bailetti, Diego, Mendonca, Christine, Mannino, Gaia Chiara, Fontana, Andrea, Andreozzi, Francesco, Hastings, Timothy, Mercuri, Luana, Alberico, Federica, Basile, Giorgio, Copetti, Massimiliano, Sesti, Giorgio, Doria, Alessandro, Trischitta, Vincenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872508/
https://ncbi.nlm.nih.gov/pubmed/26253791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.07.030
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