Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures

Age at onset of alcohol dependence (AO-AD) is a defining feature of multiple drinking typologies. AO-AD is heritable and likely shares genetic liability with other aspects of alcohol consumption. We examine whether polygenic variation in AO-AD, based on a genome-wide association study (GWAS), was as...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Kapoor, M, Chou, Y-L, Edenberg, H J, Foroud, T, Martin, N G, Madden, P A F, Wang, J C, Bertelsen, S, Wetherill, L, Brooks, A, Chan, G, Hesselbrock, V, Kuperman, S, Medland, S E, Montgomery, G, Tischfield, J, Whitfield, J B, Bierut, L J, Heath, A C, Bucholz, K K, Goate, A M, Agrawal, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872451/
https://ncbi.nlm.nih.gov/pubmed/27003187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.27
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