Reduced sleep duration mediates decreases in striatal D2/D3 receptor availability in cocaine abusers

Neuroimaging studies have documented reduced striatal dopamine D2/D3 receptor (D2/D3R) availability in cocaine abusers, which has been associated with impaired prefrontal activity and vulnerability for relapse. However, the mechanism(s) underlying the decreases in D2/D3R remain poorly understood. Re...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Wiers, C E, Shumay, E, Cabrera, E, Shokri-Kojori, E, Gladwin, T E, Skarda, E, Cunningham, S I, Kim, S W, Wong, T C, Tomasi, D, Wang, G-J, Volkow, N D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872440/
https://ncbi.nlm.nih.gov/pubmed/26954979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.14
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