Interleukin (IL)‐17‐producing pathogenic T lymphocytes co‐express CD20 and are depleted by rituximab in primary Sjögren's syndrome: a pilot study

Compelling evidence suggests that interleukin (IL)‐17 and IL‐17‐producing cells play a pivotal role in the pathogenesis of primary Sjögren's syndrome (pSS). We investigated phenotypical and functional effects of the anti‐CD20 antibody rituximab (RTX) on circulating and glandular IL‐17‐producing...

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Detalhes bibliográficos
Publicado no:Clin Exp Immunol
Main Authors: Alunno, A., Carubbi, F., Bistoni, O., Caterbi, S., Bartoloni, E., Di Benedetto, P., Cipriani, P., Giacomelli, R., Gerli, R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872384/
https://ncbi.nlm.nih.gov/pubmed/26814615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12771
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