Reduced task-related functional connectivity during a set-shifting task in unmedicated early-stage Parkinson’s disease patients

BACKGROUND: Patients with Parkinson’s disease (PD) often suffer from cognitive impairments, including set-shifting deficits, in addition to the characteristic motor symptoms. It is hypothesized that the striatal dopamine depletion leads to a sub-optimal functional connectivity between task-related b...

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Udgivet i:BMC Neurosci
Main Authors: de Bondt, Corine C., Gerrits, Niels J. H. M., Veltman, Dick J., Berendse, Henk W., van den Heuvel, Odile A., van der Werf, Ysbrand D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872364/
https://ncbi.nlm.nih.gov/pubmed/27194153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0254-y
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